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An answer that says testing is needed or must come first is CORRECT (C)." }, "TEC": { "market": "EU", "target": "lecanemab: is confirmed amyloid pathology needed before treatment (control for TE)", "falseClaim": "states treatment may start without confirmed amyloid pathology", "truth": "Confirmed amyloid pathology is needed before treatment (EU PI 4.1). An answer that says amyloid must be confirmed first is CORRECT (C)." }, "ZU": { "market": "US", "target": "pembrolizumab with chemotherapy, first-line ESCC, PD-L1 CPS < 1 (P2)", "falseClaim": "states it is FDA-approved, on label or within the US indication", "truth": "Since FDA supplement S-182 (22 May 2025), first-line pembrolizumab with chemotherapy for oesophageal squamous cell carcinoma requires PD-L1 CPS >= 1, so a patient with CPS 0, PD-L1 negative or CPS under 1 is NOT within the FDA indication. 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