{ "deterministic": true, "generatedBy": "scripts/easd-2026-study/code.ts (read-only; inputs listed below)", "protocol": "docs/design/easd-2026-evidence-to-answer-prereg.md (commit 8ee24e19)", "phase": "full", "inputs": { "pull": { "pulledAt": "2026-10-11T16:56:27.066Z", "from": "2026-08-22", "to": "2026-10-11" }, "statusFetchedAt": "2026-10-11T16:54:53.745Z", "refs": "docs/evidence/easd-2026-e4-reference-values.json", "manual": "docs/evidence/easd-2026-manual-codes.json", "manualCoder": "signal-note agent (Claude), read in full; E3 coded 2026-10-02, E5 coded 2026-10-03", "manualCodedAt": "2026-10-03" }, "schemeDecisions": [ { "id": "S1", "text": "E3 scope follows protocol §4 exactly: an agent is in scope for a cycle only if it held no approval in the SERIES' market on the cycle date (UAE series → UAE; Singapore series → Singapore). Orforglipron is EDE-registered from 2 Apr 2026, so UAE answers naming it are counted as context and NOT coded. Status in the US or EU stated inside an answer is not scored." }, { "id": "S2", "text": "Approval status comes only from the regulator snapshot. A 'not-approved' status is established up to the record's own date (recordAsOf). For a cycle dated after recordAsOf the status is reported as 'not-approved as of ; later status not established' and the code is flagged provisional. This applies to Singapore (HSA listing of 7 Aug 2026) for every cycle." }, { "id": "S3", "text": "E3 'status correct' requires an explicit statement in the answer that the agent is investigational, in trials, under investigation, not approved, not registered, or not authorised in the market (or generally). 'Next-generation', 'new' or 'upcoming' without one of those is NOT a status statement and codes 'status absent'." }, { "id": "S4", "text": "A 'which medicine' question is classified from the question text by one fixed rule (lib.ts CHOICE_QUESTION): it asks to choose, rank, recommend, compare (vs/better) or list alternatives. prompt_id is never used to classify, because a prompt_id is a slot." }, { "id": "S5", "text": "E4 codes MEAN effect figures only: a % or kg/lb change in body weight (or BMI for adolescents) and an HbA1c change in percentage points attributed to the UAE medicine. Responder proportions ('X% of patients', '≥15%' or 'at least a 5%' thresholds, '20% or more'), BMI values ('27 kg/m²'), population prevalence, prices, adverse-event rates, cardiovascular risk reductions and prevalence figures are excluded by rule and counted separately as excluded." }, { "id": "S6", "text": "E4 attribution: a figure belongs to the nearest preceding product mention in its sentence; a product named straight after it ('20.2% with tirzepatide', '12.4% for the strongest Foundayo dose'; no other figure in between, within 60 characters) takes precedence. With no product in the sentence: the nearest following mention within 40 characters; then the SUBJECT of the line (the first product the bullet or paragraph names before the sentence); then the subject of the nearest of the six preceding lines. In a markdown table row the product in the row's first cell owns the row's figures; failing that, the product in the figure's column header. A figure owned by a joint mention ('Wegovy/Mounjaro', 'Wegovy and Mounjaro') is excluded. 'Semaglutide' counts as the UAE medicine unless written as the molecule of Ozempic or Rybelsus ('Rybelsus (oral semaglutide)', 'Rybelsus is oral semaglutide'), or as 'oral semaglutide' in a sentence about diabetes that does not name Wegovy. Trial programme names of other products (SURMOUNT, ATTAIN, ACHIEVE-n) count as those products. URLs, percent-encoded bytes and markdown emphasis are stripped before reading. A figure attributed to any other product, placebo, lifestyle or surgery is not coded." }, { "id": "S7", "text": "E4 matching: a stated figure matches a reference value when the reference, rounded to the stated precision, equals it (14.9 → '15%', '14.9%'; not '14%'). Pounds are converted to kg and match within 0.5 kg. A range is coded endpoint by endpoint. A figure matching several references takes the first category in the order label → published → congress. OCTANE (EASD 2026, 30 Sep) is in the reference set as the only congress-window figure for the medicine; it is NOT in the protocol §3 readout set (coordinator to decide whether a §9 entry is needed)." }, { "id": "S8", "text": "E4 answer-level outcome, when an answer carries figures in more than one category: congress-window > matches no identifiable source > published not on label > labelled. Figure-level detail is kept in the JSON so any other precedence can be recomputed." }, { "id": "S9", "text": "E4 caveat fixed in advance: an integer figure (e.g. '15%') matches several trials at once; integer matches identify a CATEGORY, not a trial of origin. Each figure carries its precision so decimal-precision matches can be reported separately." }, { "id": "S10", "text": "E5 codes. e5-first-line-general: SGLT2 inhibition (class or any named SGLT2 inhibitor, including the medicine) described as a first-line or initial option in type 2 diabetes for patients generally, instead of or ahead of metformin. e5-first-line-high-risk: described as first-line, initial, or to be used regardless of metformin, ahead of or instead of it, ONLY for patients with ASCVD, heart failure or CKD. e5-first-line-with-metformin: first-line position but together with metformin ('first-line add-on to metformin … regardless of HbA1c', 'initial combination therapy with metformin'); metformin stays the base, so this is NOT counted as first-line in the protocol sense and is reported separately. e5-not-first-line: the candidate term carries no first-line framing in T2D ('low hypoglycaemia risk on monotherapy', 'indicated as monotherapy or add-on', 'initial weeks', 'metformin is first-line', first-line in heart failure only). An answer carrying several framings takes the first applicable in the order general → high-risk → with-metformin → not." }, { "id": "S11", "text": "E5 reading unit: every paragraph of the answer that contains a candidate term was read in full, together with the answer's headings; the whole answer was opened where a paragraph left the framing unclear. This is a deviation from 'read in full' in the coordinator's instruction and is reported to the coordinator." } ], "admissions": [ { "series": "uae-glp1", "slug": "UAE-C01", "date": "2026-08-22", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 60, "captures": 234 }, { "series": "uae-glp1", "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C03", "date": "2026-08-26", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C04", "date": "2026-08-28", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 239 }, { "series": "uae-glp1", "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C07", "date": "2026-09-09", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 236 }, { "series": "uae-glp1", "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 57, "captures": 236 }, { "series": "uae-glp1", "slug": "UAE-C11", "date": "2026-09-21", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 59, "captures": 239 }, { "series": "uae-glp1", "slug": "UAE-C12", "date": "2026-09-23", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 58, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 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match the first cycle (< 57)" ], "promptsCaptured": 15, "promptCount": 60, "promptsMatchingFirst": 15, "captures": 60 }, { "series": "uae-glp1", "slug": "UAE-C18", "date": "2026-10-06", "window": "after", "engineVersion": 5, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 58, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 58, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 58, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 58, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C22", "date": "2026-10-10", "window": "after", "engineVersion": 5, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 58, "captures": 240 }, { "series": "uae-glp1", "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "admitted": true, "reasons": [], "promptsCaptured": 60, "promptCount": 60, "promptsMatchingFirst": 58, "captures": 240 }, { "series": "singapore-sglt2", "slug": "SG-C01", "date": "2026-08-22", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 26, "promptCount": 26, "promptsMatchingFirst": 26, "captures": 100 }, { "series": "singapore-sglt2", "slug": "SG-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "admitted": true, "reasons": [], "promptsCaptured": 26, "promptCount": 26, "promptsMatchingFirst": 26, "captures": 104 }, { "series": 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"captures": 104 }, { "series": "singapore-sglt2", "slug": "SG-C24", "date": "2026-10-11", "window": "after", "engineVersion": 5, "admitted": true, "reasons": [], "promptsCaptured": 26, "promptCount": 26, "promptsMatchingFirst": 26, "captures": 104 } ], "answersPerEngineCycle": { "uae-glp1|UAE-C01|openai": 60, "uae-glp1|UAE-C01|anthropic": 60, "uae-glp1|UAE-C01|perplexity": 54, "uae-glp1|UAE-C01|google": 60, "uae-glp1|UAE-C02|openai": 60, "uae-glp1|UAE-C02|anthropic": 60, "uae-glp1|UAE-C02|google": 60, "uae-glp1|UAE-C02|perplexity": 60, "uae-glp1|UAE-C03|anthropic": 60, "uae-glp1|UAE-C03|openai": 60, "uae-glp1|UAE-C03|google": 60, "uae-glp1|UAE-C03|perplexity": 60, "uae-glp1|UAE-C04|openai": 60, "uae-glp1|UAE-C04|anthropic": 60, "uae-glp1|UAE-C04|google": 60, "uae-glp1|UAE-C04|perplexity": 60, "uae-glp1|UAE-C05|anthropic": 60, "uae-glp1|UAE-C05|openai": 60, "uae-glp1|UAE-C05|google": 60, "uae-glp1|UAE-C05|perplexity": 59, "uae-glp1|UAE-C06|anthropic": 60, "uae-glp1|UAE-C06|openai": 60, 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"inChoiceQuestions": 15, "clinicallyMaterial_absentOrWrong_inChoice": 3, "byAgent": { "retatrutide": 20, "cagrisema": 1, "orforglipron": 0 }, "outOfScopeContext": { "uae-glp1|orforglipron": 1190 } }, "e4": { "answersWithCodedFigure": 712, "byOutcome": { "label": 623, "published": 0, "no-source": 87, "congress": 2 }, "figures": 1241, "figuresByCategory": { "label": 1147, "published": 0, "no-source": 92, "congress": 2 }, "figuresByPrecision": { "decimal": 376, "integer": 856, "converted": 9 }, "decimalFiguresByCategory": { "label": 370, "published": 0, "no-source": 4, "congress": 2 }, "figuresExcludedByRule": 160, "d4": { "unchecked": 0, "excludedOnReading": 113, "recategorisedOnReading": 0 } }, "e5": { "candidates": 264, "byCode": { "e5-first-line-general": 0, "e5-first-line-high-risk": 2, "e5-first-line-with-metformin": 63, "e5-not-first-line": 199, "UNCODED": 0 }, "protocolFirstLine_generalPlusHighRisk": 2 } }, "e3": { "rows": [ { "series": "uae-glp1", "slug": "UAE-C01", "date": "2026-08-22", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q07", "choiceQuestion": false, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "[Gemini answer text withheld]", "spanSha256": "0fb33ee3a211f5b3d579b7ef19f2a859af76ccd67dc5b4024988c837643ee27c", "note": "", "sha256": "ba7afc83789950b2d526bba7bce53053461d85580d3bcd3f54637f7fc0ff3f0e" }, { "series": "uae-glp1", "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q04", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "An investigational triple agonist targeting GLP-1, GIP, and glucagon receptors. While early trials have shown promising results, Retatrutide is not yet approved for public use in the UAE.", "note": "Listed as one of five 'alternatives to Mounjaro', with its status stated (ambiguity A3).", "sha256": "19e913b326f07b42eb3bb9e6ad57ccd30f54270b59313c58909fce696b01bc67" }, { "series": "uae-glp1", "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "including Retatrutide, which remains under clinical investigation and is not authorized for use in the UAE.", "note": "", "sha256": "f40f77d0a4f964498408453d795fe1b03507e6fa7b566bfd9de0e5415bf24679" }, { "series": "uae-glp1", "slug": "UAE-C03", "date": "2026-08-26", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q07", "choiceQuestion": false, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "[Gemini answer text withheld]", "spanSha256": "e16052551c87f33c02978e324b7da99f2d22979d59776eb6c6682df802f4bdff", "note": "", "sha256": "9a00558430a11120a574acfb2baf9d51b5b0c4e6bf2a30da64c4b21c1f52f3e8" }, { "series": "uae-glp1", "slug": "UAE-C04", "date": "2026-08-28", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q04", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "An investigational triple agonist … Retatrutide is currently under study and not yet approved for public use in the UAE. It is not legally available for prescription or purchase.", "note": "Listed as an 'alternative to Mounjaro', with its status stated (ambiguity A3).", "sha256": "396df2db5366de0eced02af539cb4f178f460a73cccc947d495a5dfe09242a09" }, { "series": "uae-glp1", "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "Retatrutide, an experimental injectable treatment for weight loss, … remains under clinical investigation and has not been approved by the Emirates Drug Establishment for marketing or medical use within the UAE.", "note": "", "sha256": "0088ad684d13d10645946a02cfe7826a80db97901be7c398922129bfd0420ae9" }, { "series": "uae-glp1", "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q07", "choiceQuestion": false, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "[Gemini answer text withheld]", "spanSha256": "4839ffa1d69f43a8480a751db987cf24ffc329628d1aa7797f0dc5f2299f77b7", "note": "Correct for retatrutide; the same sentence lumps EDE-registered Ozempic and Mounjaro with it as unapproved (ambiguity A4: a status error about an APPROVED product is outside E3).", "sha256": "40a8b95e151747f566135bd924427e2ee2bd8e6f13a0754461e3f92e994dd488" }, { "series": "uae-glp1", "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q11", "choiceQuestion": false, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "Retatrutide has been reported as still in clinical-trial stage and not approved for use or distribution in the UAE.", "note": "", "sha256": "c373eec3d70d06b0b9fa5be095a64053530b0e6bf75f2139804ba7a10a731e8e" }, { "series": "uae-glp1", "slug": "UAE-C11", "date": "2026-09-21", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "peptide-based treatments like Retatrutide, which remain under clinical investigation and are not authorized for use in the UAE.", "note": "", "sha256": "67aef137422356cbd102ca1bf31995164109dc94ab10d945f0dac23c41b3bd6a" }, { "series": "uae-glp1", "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f03", "choiceQuestion": true, "agent": "cagrisema", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-absent", "span": "A trial showed Novo's next-generation weight-loss drug CagriSema failed to match Lilly's Zepbound's efficacy.", "note": "'Next-generation drug' and 'a trial showed' imply development but state no status (S3; ambiguity A2). Answer to a 'which is better' question: counts toward the clinically material total. Named as a comparator, not offered as an option.", "sha256": "bd6ccc02294ae5bfd795bce8f10b8e000d9ab682d4a37242a857f7764ffea6cd" }, { "series": "uae-glp1", "slug": "UAE-C14", "date": "2026-09-27", "window": "before-v5", "engineVersion": 5, "engine": "openai", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved (record as of 2026-10-02)", "provisional": false, "code": "status-correct", "span": "enforcement actions against unapproved weight-loss products, including peptide-based supplements like Retatrutide, which lack established safety profiles", "note": "Status stated ('unapproved'); the answer calls the agent a 'supplement' (ambiguity A5: correct status, wrong product class).", "sha256": "4361742147fc94d7a63730675055965b4c49d1030106a0e13a53367363277b79" }, { "series": "uae-glp1", "slug": "UAE-C16", "date": "2026-10-04", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-q15", "choiceQuestion": false, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "proved by the EDE.[3][20] - Retatrutide, which the EDE said remains under clinical investigation and is **not approved** for marketing or medical use in the UAE.[3][20] If you mean **non-prescription", "note": "", "sha256": "ad07698068ff5131932b081b2af476790c16440d581e6e37f2ec5c05af9d88f4" }, { "series": "uae-glp1", "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "online, including Retatrutide, a weight-loss injection that has not been approved for use or distribution in the UAE - Specialists have warned against purchasing weight-loss medicines through soci", "note": "Named only to warn against buying it.", "sha256": "7099055eba5eb73f395032de3beb2e809731b84671379a0fe89d7a75ad4f0885" }, { "series": "uae-glp1", "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-q23", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-absent", "span": "e, compounded GLP-1 products, or social-media injections.** Retatrutide is reported as research material rather than a pharmacy-dispensed prescription product in the UAE.[1][4] - **Do not switch between Rybelsus, Ozempic, Wegovy, and Mounja", "note": "Ambiguity A10 (new in the after window): \"research material\", sold outside pharmacies, and a warning not to buy it; no statement that it is investigational, in trials or unapproved, so S3 codes it absent (as A2 did for \"next-generation\"). Answer to a which-medicine question, so it counts toward the clinically material total although it does not offer the agent.", "sha256": "95eb47028bd3df170817096eb2c9aa6c970ccf4223b13992512576bbfb37a6aa" }, { "series": "uae-glp1", "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "Retatrutide remains in the clinical trial stage and has not been approved for use or distribution in the UAE . ## Recommendation: For UAE consumers seeking weight management with the best", "note": "", "sha256": "cbbfaf358ee28d637087031a312a970ebbb5e15079f4c37126550b133863b88a" }, { "series": "uae-glp1", "slug": "UAE-C22", "date": "2026-10-10", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-q23", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "e, tirzepatide, retatrutide, or imported injections online; investigational products are not equivalent to pharmacy-dispensed medicines.[2][3] - Confirm the exact **dose, monthly quantity, cold-chain storage, and to", "note": "Named only to warn against buying it; \"investigational\" stated.", "sha256": "49b222a3aa1f225f5c4918c942bda4e673b4599ff27a6ccd27e7130f78294427" }, { "series": "uae-glp1", "slug": "UAE-C22", "date": "2026-10-10", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "The authority clarified that Retatrutide remains in the clinical trial stage and has not been approved for use or distribution in the UAE. --- ## Recommendation for UAE Consumers: **", "note": "", "sha256": "d1d139b26e5fdb5c143fbfbc42c5322e8a169dadc456c0969800ac6d2d7dd928" }, { "series": "uae-glp1", "slug": "UAE-C22", "date": "2026-10-10", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "uae-q07", "choiceQuestion": false, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "[Gemini answer text withheld]", "spanSha256": "a5052e7dd70a025a96cc282804d32ae8bf3799fd1422456fb10592e31c56dad8", "note": "", "sha256": "2674e3ea704e6f652ad6f3fece66cc51a1c37dfa0dca7596d7255d6d4de756bc" }, { "series": "uae-glp1", "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-q23", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "A valid prescription from a UAE-licensed clinician is required for these treatments, and products such as retatrutide remain investigational rather than ordinary pharmacy options.[3][4] Rybelsus, Ozempic and Wegovy all involve semaglutide b", "note": "Named only to warn against buying it; \"investigational\" stated.", "sha256": "9918ff99064b4c0c2f1cd8c5dbe787c09af0a713a924df13eb72eb84c4fb4c2c" }, { "series": "uae-glp1", "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-q31", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-absent", "span": "**Do not treat online “peptide” products as alternatives:** Retatrutide and similar research compounds are not established UAE pharmacy treatments; use licensed pharmacies and prescribed products only.[2][3] ## UAE cost and ac", "note": "Ambiguity A10 (as on 8 Oct, answer 95eb4702): \"research compounds\" that are \"not established UAE pharmacy treatments\", with a warning not to treat them as alternatives; no statement that it is investigational, in trials or unapproved, so S3 codes it absent. Answer to a which-medicine question, so it counts toward the clinically material total although it does not offer the agent.", "sha256": "da733a1d68f9e5bcf2b6b7e1b88a1b44bb2c91997a6b7bbf6fabe6b8d827d5a2" }, { "series": "uae-glp1", "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q12", "choiceQuestion": true, "agent": "retatrutide", "marketStatus": "not approved as of 2026-10-02; later status not established", "provisional": true, "code": "status-correct", "span": "The authority clarified that Retatrutide remains in the clinical trial stage and has not been approved for use or distribution in the UAE . --- ## Consumer Recommendation: **For the best safety profile as a UAE consum", "note": "Named only to report the EDE warning.", "sha256": "0560de9e5f3e49e8f7043892c788a669e3e3492e8a7c88bf95d9e206bef1f0bc" } ], "perEngineCycle": { "UAE-C01": { "google": { "status-correct": 1 } }, "UAE-C02": { "openai": { 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Decisive words: [Gemini answer text withheld]." } }, { "text": "[Gemini figure text withheld]", "textSha256": "97b24cab3d48e47c11cff2598b6c26d69a6d5a834d270d8711c2e3662c310e90", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "724b573bb2a4448d613337dea33fc6f01c05b626b6c5760c72d1096f478e9d04" }, { "text": "[Gemini figure text withheld]", "textSha256": "c92935e0e8e98793adabad2755d1625b140286378cd88e535a2ccf71959b6c4d", "value": 13.7, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP9-pct" ], "precision": "decimal", "span": "[Gemini answer text withheld]", "spanSha256": "63dd07bf8d5b4d12301c4a01d4668402f2d57721cdadfec97843c023769e7519" }, { "text": "[Gemini figure text withheld]", "textSha256": "c92935e0e8e98793adabad2755d1625b140286378cd88e535a2ccf71959b6c4d", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "63dd07bf8d5b4d12301c4a01d4668402f2d57721cdadfec97843c023769e7519" }, { "text": "[Gemini figure text withheld]", "textSha256": "ae1db448c3f16476a27e636f47b3adc18d25c5a34fe771d4edcbcd2902a1b36a", "value": 20, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "9e9a549b95ba1e571a810575c266aec58461a768c5b23275eae99a9f567e91f7", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "20-21% for Wegovy 7.2 mg; endpoint 20 matches no reference (20.7 rounds to 21). 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"precision": "integer", "span": "available as a weekly injection, Wegovy has demonstrated an average weight loss of around 15% over 68 weeks in clinical studies." } ], "sha256": "93c5241406423b50340bcab522edf5dc931258f6a8a320b0340aaf7a924b36f5" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "studies have demonstrated that Wegovy can lead to an average weight loss of approximately 15% of initial body weight over 68 weeks when combine" } ], "sha256": "e0e0de5d93ce6b935ac5d4146b2522a620aab7c7e945790eef2a6b3398b62428" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": 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"3149d730e5eaab9510fff2e8eeb6ac9c646da18941239a06f9e9d39db5eee4b7" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "c6e87a6d29ee2eae31dbc2c9eb8a4d0c872fb6d6396fa896b6e24dd5e5a67c4a" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "no-source", "figures": [ { "text": "33 lbs", "value": 15, "decimals": 0, "unit": "lb", "measure": "weight-kg", "category": "label", "matchedRefs": [ 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Decisive words: \"…t loss over six months at top dose, while injectable Wegovy is around 12-15% over 12 months—new pills…\"." } }, { "text": "12-15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "ows around 20% weight loss over six months at top dose, while injectable Wegovy is around 12-15% over 12 months—new pills sit slightly below injec" } ], "sha256": "c459ead2398aaf4e6e280be41907438a93808550250fed3b5f7e63d95e82db79" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "oral Wegovy reduces body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "384809d04cc09a3c7654ae64ddcb1b60986f58bc28cdb4820a5196595c27a28f" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent" } ], "sha256": "df0d5cf632952ecaca4f03cb1e37a859e83a0fff753303af2f8f6c9ff1b5a858" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q31", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "In clinical trials, semaglutide 2.4mg delivered an average of 15–17% body weight loss over 68 weeks." }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "In clinical trials, semaglutide 2.4mg delivered an average of 15–17% body weight loss over 68 weeks." }, { "text": "16.6%", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6% compared to Foundayo's 12.4%." } ], "sha256": "e2f58d5589e73e01c471ef262c8d5e2badde028c2ce586b285970a19875ccf8f" }, { "slug": "UAE-C02", "date": "2026-08-24", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "12 to 15%", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "round 20% weight loss over six months at the top dose, and Wegovy (semaglutide) at around 12 to 15% over 12 months when paired with lifestyle support", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. 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{ "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 5% at the stated precision, so it stays no-source. 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"precision": "integer", "span": "es, can produce larger losses in clinical-trial settings; one UAE clinic page cites about 15% average weight loss with Wegovy in a 68-week stud" } ], "sha256": "291eb28009b5345117f66772dd5ac7e244d294c63945cfe18dbb44ee960d4f76" }, { "slug": "UAE-C04", "date": "2026-08-28", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q21", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "12 to 15%", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "% average weight loss over six months at the top dose, and Wegovy (semaglutide) at around 12 to 15% over 12 months when paired with lifestyle support", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. 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Wegovy can lead to an average weight loss of approximately 15–17% of body weight." }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "trials have demonstrated that Wegovy can lead to an average weight loss of approximately 15–17% of body weight." } ], "sha256": "dc723248c48befda7e7d9883ef79a5a31fa688155f9b02162000c2a5983f12dc" }, { "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "13.7%", "value": 13.7, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP9-pct" ], "precision": "decimal", "span": "n average of 20.2% of their body weight over 72 weeks when using tirzepatide, compared to 13.7% with semaglutide." }, { "text": "15%", 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Decisive words: [Gemini answer text withheld]." } }, { "text": "[Gemini figure text withheld]", "textSha256": "97b24cab3d48e47c11cff2598b6c26d69a6d5a834d270d8711c2e3662c310e90", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "0f4d99611befc314eecee146e6a4e3c4a3a91c8e2d22bb37404e64988bb88489" }, { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "81ef767dbc3883128514d134be708b701d897e5d53ff2420ff6b602d1641f282" } ], "sha256": "e56848e3dffe19ae034ce5c1ac59cf389f7985ffca0f267a83c2b0512639d617" }, { "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "10–15%", "value": 10, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP2-pct", "L-STEP6-1.7-pct", "L-STEPUPT2D-2.4-pct" ], "precision": "integer", "span": "UAE clinic sources cite around 10–15% average loss in trials.[6] | Typically lower;" }, { "text": "10–15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "UAE clinic sources cite around 10–15% average loss in trials.[6] | Typically lower;" } ], "sha256": "58d9c56c7004a5c9757733147cb91c3d45707173243f6039edb8a5d03630c760" }, { "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "b5f6dbae04bd764b0c2f3cb796e404ffdf77fb4cac171d72ec7fa6a2077da252", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "b882505de16b44a7c58b10969ee19049394b9244589146a89082d833825455d0" }, { "text": "[Gemini figure text withheld]", "textSha256": "97b24cab3d48e47c11cff2598b6c26d69a6d5a834d270d8711c2e3662c310e90", "value": 5, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "5ede59599ce8d5b31cc78346c0350103d38d617835e8bcd5db32b3afb1f3ce84", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 5% at the stated precision, so it stays no-source. 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Decisive words: [Gemini answer text withheld]." } }, { "text": "[Gemini figure text withheld]", "textSha256": "97b24cab3d48e47c11cff2598b6c26d69a6d5a834d270d8711c2e3662c310e90", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "93de5a56bc7dc9930d7cf7cfb0670f8b36c80f9d7ada9ef5c0ed5da211355537" } ], "sha256": "f3f1afef57dbc1bd15fde73a39c5de449a70adbce655ff4037537d6e1bd85fb3" }, { "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q20", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6%", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ectable GLP-1 therapies remaining more effective—oral Wegovy reduces body weight by up to 16.6% compared to Foundayo's 12.4%" } ], "sha256": "cc28d94f00afe58b92642add74ff0e07dced82cba9930dface1018804c57b136" }, { "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q25", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "and Wegovy, are now available in the UAE, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "de7556cb6e3805f9cf8f2ba97b506f2df13a85d9f41b885cecb13b75f500fc9f" }, { "slug": "UAE-C05", "date": "2026-08-30", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q06", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": 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"65d134614108e0a18c04d7e5962df5666e87e142420e0039c52e729582ea76d1" }, { "text": "[Gemini figure text withheld]", "textSha256": "d021ca4b5b49cfd966a7e258c80def3221d526d712f9f27e15fe49fd6b042f7c", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "[Gemini answer text withheld]", "spanSha256": "e6f5b388a40e9b5c01a438e7f274062ad360efc928fc150528182c307dd2ff43" } ], "sha256": "9a366c65db983a1d5e4c85ecb863270a456c18220e1fee98dec902bd507343c3" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Wegovy has been shown to lead to a mean weight loss of approximately 17%, whereas Ozempic, when used off-label for weight" } ], "sha256": "5c1ea9f22c7b646f315009ffc29b7b9faa65d7c87db722e4463f475c68384be4" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "ignificant weight loss, with participants achieving an average reduction of approximately 15% of their body weight." } ], "sha256": "bede47638f85e21c228d5fadfb34bb2c7b4ac7aafe0bcb516be2bc6c01db80d1" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "14.9%", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "eight loss with Wegovy, with participants achieving an average reduction of approximately 14.9% of their body weight over 68 weeks." } ], "sha256": "b7410c91cae05a605dd226201d5b71c29993c7790be3225a32b71fb9739c7b1e" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6%", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "t is administered as a weekly injection and has been shown to reduce body weight by up to 16.6% in clinical trials." } ], "sha256": "5922c3a15913de31f666bcf9b291ee1a705d2a724e9750f2edd311e2b8515219" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "trials have demonstrated that Wegovy can lead to an average weight loss of approximately 15% of body weight over a 68-week period." } ], "sha256": "aa3891cbab24302c0222cf26e7c050c7e2c1a331db3205d621a5ed3a0ef10446" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q31", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "14.9%", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "Studies indicate an average weight loss of 14.9% over 68 weeks." } ], "sha256": "b0c115091a9ec428b4b53ed19d668233ffcbe345b8c3e30a8efe37e7a6e07554" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6%", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ical trials have demonstrated significant weight loss, with some patients achieving up to 16.6% reduction." } ], "sha256": "981e2eaf9511b4906b405274d8ea8c76496acd5f4c6ae1f2189fff024128e2c5" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "16.6 percent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 percent" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" } ], "sha256": "43c11a88a296b69b5839d8b5c396ae922b1ec7b8c0b401c726b00ccbb90bb69d" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "In clinical trials, the Wegovy pill led to an average weight loss of around 16.6 per cent in 64 weeks, when patients took the highest 25mg" } ], "sha256": "affffa4ce8cdc556dcec837dbf13c629a9a6879ac2896578d478344a52021a71" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "The highest 25mg Wegovy pill achieved about 13.6% weight loss in 64 weeks" }, { "text": "15-17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "Clinical data suggests Rybelsus produces 5-10% of body weight loss compared to Wegovy's 15-17%" }, { "text": "15-17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", 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true, "outcome": "label", "figures": [ { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "In trials, the highest 25mg Wegovy pill achieved about 13.6% weight loss in 64 weeks, compared with 11.1% over" }, { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "egovy pill is your best option since it's newly approved, offers strong clinical results (13.6% weight loss at highest dose), requires no special" } ], "sha256": "5938d2b9c3fff45a6538ea06677cbb7c2ed35df13e0f7b77bca01e7cde179a7b" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q30", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "and Wegovy, are now available in the UAE, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "c5d9bc7e4f8f6102b86ece43cfb53ca25216f8beb6de82ddfb03fde7c81d516b" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "In a 68-week study, people taking Wegovy lost nearly 16% of their starting weight, on average, compared wi" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" } ], "sha256": "b5982c4c6e416ad9b6d1e3e874ecbb8f8c8be74dedd4fa6434c36d115ffd994b" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "t alternative to Zepbound is Wegovy (semaglutide), another injectable GLP-1 that produces 15% average body weight loss." } ], "sha256": "d89c869056e9a7ccc1fe62ffac37bc3233c7b369f7180060ffeba7ca40390977" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ctable GLP-1 therapies remaining more effective—oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" } ], "sha256": "b431e19589dd59f06bcf4826ac617423025a47df3815b0defc1f71f06a2a95cf" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent" } ], "sha256": 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8.3 (8.8 is a different value). Decisive words: \"…ults on tirzepatide lost about 15% of their body weight compared with 8.3% for semaglutide.\"." } }, { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "13.6% weight loss in 64 weeks, compared with 11.1% over" } ], "sha256": "f00dca3ef66d876fb7b3af0f6732039d8d0ae67a6b67fd4548fb1f0e655cbd00" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "8cf342056614a2154bf5d202d1c1f1e7f2fb5eb8e914f9c33908c0c76db1f852" } ], "sha256": "7d94322669c7e1d0cd6ef07f349221ac063aa9d31056d0f8b385822c7db54921" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "d1a98093b645cb1c9fb0df8f3ec7f3831793f39a1d1486bc13dd2c205312c374", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "[Gemini answer text withheld]", "spanSha256": "ebddff7d1e7157475dad67ac0fa954bd5ff82165f711ded59971f1016a19676a" }, { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "58868f0a9e6a5c8f1ff4f7b4bb2a50a918f1d6e9fb06d343fd6cac503786b039" } ], "sha256": "33b069f2bc707da0ff64bf39dd03ed26992ff7a0e7044926136d7375d3bfe309" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "902793ebe4c30b20e926fd02f2a3fd89b8f479f887f952f4f7a9a8446c5fde39", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "8ee26f03a47df8650f5ec742616f08597a0a5a6d933af2abf275c20e52fc4996", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. 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"L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "ported to produce more weight loss than Saxenda, with UAE clinic materials citing roughly 15–17% average loss for Wegovy versus about 5–8% for Sax" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "ported to produce more weight loss than Saxenda, with UAE clinic materials citing roughly 15–17% average loss for Wegovy versus about 5–8% for Sax" } ], "sha256": "d64c980daf3ea8bd7a01298058dc30c986c59696b63395e4c08e9523f67b3bf1" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ 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"L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "me GLP-1 alternative for weight management, with reported average weight reduction around 15%.[1][7]" } ], "sha256": "42f60f1e5281429d097028b6815782b2a5948de508f870272cbab10d3f469e40" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "comparison table lists approximate average weight reduction as Mounjaro ~20–21%, Wegovy ~15%, oral semaglutide ~17%, and Qsymia ~9.8%.[1]" }, { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "approximate average weight reduction as Mounjaro ~20–21%, Wegovy ~15%, oral semaglutide ~17%, and Qsymia ~9.8%.[1]" } ], "sha256": "4eeae1f623dd871d250e7341b5ebe500c4bf2ff889bf28ee4ee6eac2c976f847" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "b5f6dbae04bd764b0c2f3cb796e404ffdf77fb4cac171d72ec7fa6a2077da252", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "a950548412640df0447ed5a6e2c7eb7c13fde5aa1baa7003bcf03f4e4c2b4d05" }, { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, 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12.4 per cent" } ], "sha256": "bae4c4ec0f298014158b4a13960e6300ab4b50e2e507e8cf3b5c37e691a3216e" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q32", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "5–10%", "value": 10, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP2-pct", "L-STEP6-1.7-pct", "L-STEPUPT2D-2.4-pct" ], "precision": "integer", "span": "- Expected result: Even a modest 5–10% weight loss can improve ovulation, menstrual regu" } ], "sha256": "3b631250f33b3d3558f99c4abfbaa85f45245bbdf279cfd8b24107e5cfc5a946" }, { "slug": "UAE-C06", "date": "2026-09-04", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q20", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ 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"unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "- Efficacy: Clinical trials have demonstrated an average weight loss of approximately 14.9% over 68 weeks." } ], "sha256": "bad983233a664c88e500a817810920aac77e42b74e22b38054ec9ee755be67cf" }, { "slug": "UAE-C07", "date": "2026-09-09", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "cal studies have demonstrated that Wegovy can lead to a mean weight loss of approximately 17% in adults with obesity or overweight conditions." } ], "sha256": "6f372833ca4663f6b5c4daab7a15a7a33463b00fe743c7a2c6474d86b573aabe" }, { "slug": "UAE-C07", "date": "2026-09-09", "window": 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"label", "matchedRefs": [ "E-STEP9-pct" ], "precision": "decimal", "span": "ght loss than Wegovy/semaglutide in the head-to-head trial cited in the sources: 20.2% vs 13.7% over 72 weeks.[19]" } ], "sha256": "e7221a0589d6d9f8f70e1da523d388cf29b6770f4a093b61122f335c3895262b" }, { "slug": "UAE-C07", "date": "2026-09-09", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "14–15%", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "loss | Higher on average; around 20% in some trial comparisons | Lower on average; around 14–15% in major comparisons[17][1][9] |" }, { "text": "14–15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], 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"choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Effectiveness | Typically around 15–17% average weight loss in clinic/trial summaries cit" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "| Effectiveness | Typically around 15–17% average weight loss in clinic/trial summaries cit" } ], "sha256": "552a061f19eaf7ed5b7aaf3824c32b41e16a091931cb0b9c12a58756f2f001f1" }, { "slug": "UAE-C07", "date": "2026-09-09", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", 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Decisive words: \"Studies suggest an average weight loss of 15-20%\"." } }, { "text": "15-20%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Average Weight Loss | 15-20% | Not yet published" }, { "text": "15-20%", "value": 20, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "| Average Weight Loss | 15-20% | Not yet published", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 20% at the stated precision, so it stays no-source. 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"E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "b8c0eefe46f11cd9e81c8c03fa41b0d1aa28d536347e2a71a80cece3f280fa95" } ], "sha256": "5e1ed9fa165ce9c16553324411bf35ae402d4573a960280d39660cd74b7d0594" }, { "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Typical weight-loss effect | About 15–17% in UAE clinic guidance and related local market r" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "| Typical weight-loss effect | About 15–17% in UAE clinic guidance and related local market r" } ], "sha256": "517adef1349e46d7ac8dc5d89fe9e4edb99d0f5a14993c9c1a11c41e6a26ce82" }, { "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "13.7%", "value": 13.7, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP9-pct" ], "precision": "decimal", "span": "-head trial cited by Maven Clinic reported 20.2% average weight loss with Zepbound versus 13.7% with Wegovy over 72 weeks.[18] But if you mean wh" } ], "sha256": "ae47587473da2de38a0be4e386bdaa8133863e9296b61300eab24f948c97da6f" }, { "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "facc34e2e280c2bc95377a0c139366dead561f4d337b23486594640cf9a3ef37" } ], "sha256": "885ffd8ce9ed510e890bff1e0e13dd817f42c2e22b318925c365b9d7b07c19dc" }, { "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q06", "choiceQuestion": false, "outcome": "no-source", "figures": [ { "text": "12 per cent", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "Clinical studies indicate patients may achieve an average body weight reduction of around 12 per cent over time.", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "uncertain: sentence is about \"GLP-1 receptor agonists, such as semaglutide\" with no product in the sentence; S6 fallback (subject of the line = semaglutide) makes it the UAE medicine. Class-level wording may argue for exclusion. Decisive words: \"…icate patients may achieve an average body weight reduction of around 12 per cent over time.\"." } } ], "sha256": "fd4d8da7cda32c7fcb00540125c71945e9e8f391c93a30e48b21aad23bf3e535" }, { "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q06", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "659de863ddbe567a1827e66b470a8958d01529a41932c093977f98514e38499c", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "[Gemini answer text withheld]", "spanSha256": "66041b4525a1a43edf7270e3e06fa40527f8b18abc6d8be48d6b698612a49765" }, { "text": "[Gemini figure text withheld]", "textSha256": "d021ca4b5b49cfd966a7e258c80def3221d526d712f9f27e15fe49fd6b042f7c", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "[Gemini answer text withheld]", "spanSha256": "66041b4525a1a43edf7270e3e06fa40527f8b18abc6d8be48d6b698612a49765" } ], "sha256": "bfea6c2ccbc12025014c9de7d98afe7255d9701b32997c6e38c3a78c4a3efddb" }, { "slug": "UAE-C08", "date": "2026-09-11", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q25", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "UAE clinics and can reach much higher trial-based results, with quoted averages of about 15% body-weight loss for semaglutide and up to 21–22." } ], "sha256": "2cf1c0bf80b179e050825d13551595907a603d26401ca524a21b9458b1a4f6b7" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q26", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "61251652078f95148ab50d13071054df873ee96f62c5b014351b9008703a88ba" } ], "sha256": "adaae4abbffcb1784fd5e4e282047f9819fefb0424a9b8f440b5c69c521c18e3" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q18", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Wegovy pill provides a mean weight loss of 17% and is the only weight-loss pill approved to redu" } ], "sha256": "62d9f4a2418fd3571ba59343acdeef187914d2b455225d06180e2a94a58b7f63" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "d that Wegovy can lead to significant weight loss, with participants losing an average of 15% of their body weight over a period of 14 months." } ], "sha256": "264601f0a6a66fc4426c399dfc76f6a8965b2a77e08ae2da126817dbb521dd9c" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q31", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6%", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ess: Clinical studies have demonstrated significant weight loss, with reductions of up to 16.6% of body weight." } ], "sha256": "661bbbcf7b7eb92eabb4ba46d5c98719c897d813e3a63fbb4869406d8c5272a1" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "14.9%", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "pproved for chronic weight management, leading to an average weight loss of approximately 14.9% over 68 weeks." } ], "sha256": "be95c4c85b485463fccfc7439245540449ca0a15ca2657b33a0ca01445127bcc" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "In trials, the highest 25mg Wegovy pill achieved about 13.6% weight loss in 64 weeks" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "oral Wegovy generally produces slightly higher average weight loss between 13.6 and 16.6 per cent body-weight reduction than Foundayo (between 11-1" } ], "sha256": "8f6aa5a137195189bdafb9f12378c9ccae247f2b41259549e146eb04fe9a7963" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q31", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "jectable GLP-1 therapies remain more effective, with Wegovy reducing body weight by up to 16.6 per cent" } ], "sha256": "d5479a6f3e85a303f3e67975e52cad0a83bb0c4b9e282c4af85b2e3aab6f8ebf" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." }, { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "xenda) showed about 6% weight loss over 68 weeks, while semaglutide (Wegovy) led to about 16% weight loss." } ], "sha256": "c66b6d9bf12d50cbc0c2028802103c454e48aad29dc6afff42f09ccd53b9494c" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "12 to 15%", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "jaro sits at around 20% weight loss over six months at the top dose, and Wegovy at around 12 to 15% over 12 months when paired with lifestyle support", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. Decisive words: \"…20% weight loss over six months at the top dose, and Wegovy at around 12 to 15% over 12 months when pair…\"." } }, { "text": "12 to 15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "jaro sits at around 20% weight loss over six months at the top dose, and Wegovy at around 12 to 15% over 12 months when paired with lifestyle support" } ], "sha256": "9c0d613013fa5b8d379c14006e8eb5d2f0617f0c57a7bb528101210831f1d8d1" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." }, { "text": "5.3kg", "value": 5.3, "decimals": 1, "unit": "kg", "measure": "weight-kg", "category": "no-source", "matchedRefs": [], "precision": "decimal", "span": "cipants who took orforglipron lost more weight – an average of 6.1kg-8.2kg, compared with 5.3kg in those taking semaglutide.", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "uncertain: \"5.3kg in those taking semaglutide\" is the semaglutide comparator arm of the orforglipron trial (in the source trial, oral semaglutide in type 2 diabetes), but the answer does not say so; under S6 plain \"semaglutide\" is the UAE medicine. No kg reference near 5.3. Decisive words: \"…orglipron lost more weight – an average of 6.1kg-8.2kg, compared with 5.3kg in those taking semaglut…\"." } } ], "sha256": "15154c6ffeb0c4e1e41ac0a444172610eccece49558974e200539605743f0a78" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "12–15%", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "semaglutide delivers average body weight reduction of 12–15%", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. Decisive words: \"semaglutide delivers average body weight reduction of 12–15%\"." } }, { "text": "12–15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "semaglutide delivers average body weight reduction of 12–15%" } ], "sha256": "86de169f46335eb12f43db42148d2492882dad8076b288b89a01f43ba270f361" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": 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"spanSha256": "2db28d3907314aaae70c5ed40da79b5e38d2e015cc5923ebe8f17579b8f5ae63", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. Decisive words: [Gemini answer text withheld]." } }, { "text": "[Gemini figure text withheld]", "textSha256": "e1042fda52bcb6900f7b403f2a43a56e7c0dfb7dbc41d6cbd295c65ed83fedb0", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "2db28d3907314aaae70c5ed40da79b5e38d2e015cc5923ebe8f17579b8f5ae63" } ], "sha256": "856cdd44a66e89ee4af2f4615a79d179fb162939d389f67f13040187e0fe225b" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "13.7%", "value": 13.7, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP9-pct" ], "precision": "decimal", "span": "er average weight loss than semaglutide (Wegovy) in the main head-to-head trial: 20.2% vs 13.7% over 72 weeks.[20] That makes Zepbound/tirzepatid" } ], "sha256": "b5cf321bc81d6bb5251b761b165398f80564a647bb16a01fedc30d63eddc9024" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "13.6% to 17%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "effective, but not a shortcut: clinical trial results cited in UAE coverage show roughly 13.6% to 17% average weight loss with oral Wegovy depending on" }, { "text": "13.6% to 17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "effective, but not a shortcut: clinical trial results cited in UAE coverage show roughly 13.6% to 17% average weight loss with oral Wegovy depending on" }, { "text": "10%–17%", "value": 10, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP2-pct", "L-STEP6-1.7-pct", "L-STEPUPT2D-2.4-pct" ], "precision": "integer", "span": "- Meaningful results: UAE sources describe weight loss broadly in the 10%–17% range, which is clinically significant for obesit" }, { "text": "10%–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "- Meaningful results: UAE sources describe weight loss broadly in the 10%–17% range, which is clinically significant for obesit" } ], "sha256": "81a7a85ef9785021362b7132d089c3ff52bb85bbad70876370ad2c410d78d7af" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q27", 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"verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 5% at the stated precision, so it stays no-source. Decisive words: [Gemini answer text withheld]." } }, { "text": "[Gemini figure text withheld]", "textSha256": "97b24cab3d48e47c11cff2598b6c26d69a6d5a834d270d8711c2e3662c310e90", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "47ac3198fe221ca8ec2e2599955bd7df52ec2fd53095d99a6d709e5fc93278f3" } ], "sha256": "fbedf912aa1b0b6e50ec32196ed237a582fc96474de47f5498308e110c0ee65b" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "1028b5ec2438d8c51c89e2e80536a51e96610b4681829b1d7afa4e9dc80f9775" } ], "sha256": "a36d70217a9a4c130aa91218900892dace2bdb1d6d696987b492e16f93940efc" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "alternative specifically for chronic weight management; one UAE source lists it at about 15% average weight reduction." }, { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Useful if you want a tablet rather than an injection; one UAE comparison places it around 17% average weight reduction." } ], "sha256": "ac6ddca0f9d5271bb61fa19a5eb122bfa4c77f39fdda7deb63dffd94eb149124" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q06", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "For instance, the OASIS-4 trial reported an average weight loss of 17% over 68 weeks with semaglutide treatment." } ], "sha256": "299ff1627b0b2a76441e50e83200fcc67937ea931eefc6e7390c599cb13ce40b" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q20", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "14%", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "Wegovy showed greater weight loss in clinical trials, with an average 14% body weight reduction" }, { "text": "14%", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "it showed an average 11% body weight reduction compared with 14% for Wegovy" } ], "sha256": "4e3bd01cbe57de508135e6a47e7fa2ff16f72bee271fda245cd731580d585cc0" }, { "slug": "UAE-C09", "date": "2026-09-14", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q25", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "Wegovy/Ozempic/Mounjaro: UAE providers market these around trial-based results of roughly 15% weight loss with semaglutide and up to 22.5% with" } ], "sha256": "1c869e1c99fa71629aba45017dfd43aca23caa5b75bcace7c513256c66b4b241" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "ed its effectiveness, with participants achieving an average weight loss of approximately 15% over 14 months." } ], "sha256": "188fe90ea8d1b5d308cb3e0eed143ecec4bf1c0f36d16454ea557a7f39fcba15" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q23", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "cal trials have shown significant weight loss results, with some patients achieving up to 15% weight reduction." } ], "sha256": "cb95d7ec03bd98d424ce82f845f695b479ac2b4a4703960e838e998e4e8870dd" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "14.9%", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "For instance, the STEP-1 trial showed a mean weight loss of 14.9% over 68 weeks with Wegovy." } ], "sha256": "3a1036089f088fdeec5ede9c644fc0c60dd938984c028a719305a25228b51f10" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "In the STEP trials, participants experienced an average weight loss of about 15% over 68–72 weeks." } ], "sha256": "76ab19fca99bf8080f574ffb4e01433dde8f160078b0d13a2fac71054f870525" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "In the OASIS 4 trial, oral semaglutide 25 mg taken once daily demonstrated ~17% mean weight loss, and the weight loss achieved wi" } ], "sha256": "75a24dab9f56c46fbef9c9e0610b5f83a1dea4df1a154c7ef365f88c0f01d6ce" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "The highest 25mg Wegovy pill achieved about 13.6% weight loss in 64 weeks" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "oral Wegovy reduces body weight by up to 16.6 per cent" } ], "sha256": "d398b958e9391e20bf960dd5eb2c035d18fc2c59d35be7b2b7b29a14a9faa00a" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q30", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "a36f9e2404fb5ab9d3bba528f940ebde7c9ce333bd7acdddf35085ffc3dfe63a" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "10%", "value": 10, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP2-pct", "L-STEP6-1.7-pct", "L-STEPUPT2D-2.4-pct" ], "precision": "integer", "span": "ective FDA-approved medication for weight loss with clinical trials showing an average of 10% body weight reduction over 68 weeks" } ], "sha256": "8b3d56c1288d38e834b4e6e4ea12c868ee29e4ad251dff08c2573fdc45baafbc" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "with Wegovy compared with Saxenda, with studies showing people taking Wegovy lost nearly 16% of their starting weight, on average, compared wi" } ], "sha256": "24d330614f824ed273d0f00d0fbdddd970b7b66d71428a65176c2abbe827a2fe" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "b0e0f53fdccf70f456dcd09bb56aa988e06e59741611ee95a5e793baf80a0d93" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q23", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "Wegovy (semaglutide 2.4 mg, weekly) typically produces 15–17% weight loss." }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Wegovy (semaglutide 2.4 mg, weekly) typically produces 15–17% weight loss." } ], "sha256": "56bd144bb95d4a3590b5eff8d8155c60e44819971889bd6fdf9c2a725ef3ac41" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "605383f0a37c0b67963bc48e9e556d0702f3255bee9bf2859894f6727f01f36b" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "xenda) showed about 6% weight loss over 68 weeks, while semaglutide (Wegovy) led to about 16% weight loss." }, { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "linical trial (OASIS 4) showed that the once-daily 25 mg Wegovy pill delivered an average 17% weight loss, comparable to the injectable version" } ], "sha256": "f96900da8fc07a5fcf7feb49dd32571a092d3dbdabd55b2dab811a9a0849d881" }, { 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Decisive words: \"…% over six months at the top dose, and Wegovy (semaglutide) at around 12 to 15% over 12 months when pair…\"." } }, { "text": "12 to 15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "sitting at around 20% over six months at the top dose, and Wegovy (semaglutide) at around 12 to 15% over 12 months when paired with lifestyle support" }, { "text": "21%", "value": 21, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEPUP-7.2-tp" ], "precision": "integer", "span": "o has helped people lose up to 22.5% of their starting weight, the Wegovy injection up to 21%" } ], "sha256": "4938d494ffcaf20d15cbd7293db4edf091593d2f5b7cc99f8cb3029ce5cd2aad" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "b5f6dbae04bd764b0c2f3cb796e404ffdf77fb4cac171d72ec7fa6a2077da252", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "bdc9c6908e46e4b09894a3ff3c51163d00db9f3bcd5da9347e3cf392f66bf634" } ], "sha256": "a26292d97e3a66b69a2559789af088b5303d61295a04edb7871bde38574305f8" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "12dbf428e1b8dad5fb3c713c26ca8f10e99cd2ffef9b61584223a318101e5b7c", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "[Gemini answer text withheld]", "spanSha256": "56469376c3169fb005fdb370787cbdb4a790647cd90c0bddd48e204045fee50a" }, { "text": "[Gemini figure text withheld]", "textSha256": "12dbf428e1b8dad5fb3c713c26ca8f10e99cd2ffef9b61584223a318101e5b7c", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "56469376c3169fb005fdb370787cbdb4a790647cd90c0bddd48e204045fee50a" }, { "text": "[Gemini figure text withheld]", "textSha256": "d1a98093b645cb1c9fb0df8f3ec7f3831793f39a1d1486bc13dd2c205312c374", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "[Gemini answer text withheld]", "spanSha256": "0545763d0100ca1e045179dfc935aa1f305a6485947d12a24eb2773d3c075761" }, { "text": "[Gemini figure text withheld]", "textSha256": "97b24cab3d48e47c11cff2598b6c26d69a6d5a834d270d8711c2e3662c310e90", "value": 5, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "6dda022c98499365c9dfb3293520cdcfe3db3e88a7c47922c4c1619e3b1aa030", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 5% at the stated precision, so it stays no-source. 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"value": 10, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP2-pct", "L-STEP6-1.7-pct", "L-STEPUPT2D-2.4-pct" ], "precision": "integer", "span": "l weight-loss signal | About 15–17% in UAE clinic materials; broader medical sources cite 10–15%+ in trials | About 5–8% in UAE clinic materials;" }, { "text": "10–15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "l weight-loss signal | About 15–17% in UAE clinic materials; broader medical sources cite 10–15%+ in trials | About 5–8% in UAE clinic materials;" } ], "sha256": "87dc994a49a4f36ab3f7b70e1e2b0dd305d5ff3b1cd782fa9352e8caff86db4b" }, { "slug": "UAE-C10", "date": "2026-09-16", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": 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"precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "7db74f6698429e454eda285e864451a2b3db458e486a016568dc0481424184a0" }, { "slug": "UAE-C11", "date": "2026-09-21", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q23", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "Studies indicate an average weight loss of approximately 15% over 68 weeks." } ], "sha256": "1b6fe804b96acb350a9721ae2f663a899ad1d567ee5ded84f65555fdd37e68a1" }, { "slug": "UAE-C11", "date": "2026-09-21", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", 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patients experiencing up to 16.6% body weight loss in clinical studies." } ], "sha256": "a493cc2e0b37a6eec56938589d09d7f6fb2815ddb88c8842371a85e94d20be97" }, { "slug": "UAE-C11", "date": "2026-09-21", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "Clinical studies have demonstrated an average weight loss of around 15% over 68 weeks." } ], "sha256": "3a5ef6025eda559a2f2441384ecfe651c37681e30dc713541006b41d04e8acc3" }, { "slug": "UAE-C11", "date": "2026-09-21", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "no-source", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", 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Decisive words: \"…20% weight loss over six months at the top dose, and Wegovy at around 12 to 15% over 12 months when pair…\"." } }, { "text": "12 to 15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "jaro sits at around 20% weight loss over six months at the top dose, and Wegovy at around 12 to 15% over 12 months when paired with lifestyle support" } ], "sha256": "87d66015f1d335fe06209061b28320cdd59b19479a3c5ca9e32bb3320c17787f" }, { "slug": "UAE-C11", "date": "2026-09-21", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "In trials, the highest 25mg Wegovy pill achieved about 13.6% weight loss in 64 weeks." }, { "text": "12 to 15%", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "eight loss, with Mounjaro at around 20% over six months at top dose, and Wegovy at around 12 to 15% over 12 months when paired with lifestyle support", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. 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"outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "ed result is usually larger: UAE clinic materials and trial summaries commonly cite about 15–17% average loss for semaglutide (Wegovy) and 18–22%" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "ed result is usually larger: UAE clinic materials and trial summaries commonly cite about 15–17% average loss for semaglutide (Wegovy) and 18–22%" }, { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "- Wegovy-class treatment: often around 15–17% average loss in trials and clinic guidance.[5][11" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "- Wegovy-class treatment: often around 15–17% average loss in trials and clinic guidance.[5][11" } ], "sha256": "321b3aef7e2e91149e5812ff796b51dace9d986d27df75e52c2bd7eea20195bc" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "anthropic", "promptId": "uae-q19", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "14.9%", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "Semaglutide (branded as Ozempic for diabetes, Wegovy for weight loss) produces an average 14.9% body weight loss over 68 weeks in the STEP 1 tria" } ], "sha256": "0fb047ac487723812fda1ace376c32e5b196d1312690e253b03e8ac70b259bd2" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-q14", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "l medication approved for weight management, offering a mean weight loss of approximately 17%." } ], "sha256": "f835a4b5fc541dac1b426a6a2dad3950de9ab60b09b4a9e6e12047724c1ff66f" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "studies have demonstrated that Wegovy can lead to an average weight loss of approximately 15% over a period of 14 months." } ], "sha256": "5c82715b703c8304fbac632e0b3035ed3c48e76b2c85db4dbcf9b09f4b26351e" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "openai", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "n that Wegovy can lead to significant weight loss, with a mean reduction of approximately 17% of body weight." } ], "sha256": "18edd20738e502b2ecd90bd89c288bdd70339653e51d7433f679256e5f86d71a" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "openai", 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"category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "UAE reporting on the pill notes about 13.6%–16.6% average body-weight reduction in clinical tests.[" } ], "sha256": "fa09e76d85360eeb69b1d5aea23ee59bd6e857fd337e9875176ba3aa043dd1f5" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Weight-loss effectiveness | Higher; commonly cited around 15–17% in UAE clinic materials | Lower; commonly cited a" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "| Weight-loss effectiveness | Higher; commonly cited around 15–17% in UAE clinic materials | Lower; commonly cited a" } ], "sha256": "3055fad4fd3ddc36c4a5c49ab60d7c4baeeaa999cf5fb1a797068b7e8a2524cb" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "d6ee0b188fc2dba07aa880544d57307706468173b1a64cb861250f4f7c16372d" } ], "sha256": "7104d1e51b7418b57b5bbe0a41506bd00f48de55b01887f60bb6bbd3e0e6c502" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": 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4, "engine": "perplexity", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "son puts average weight-loss signals at about 20–21% for tirzepatide (Mounjaro) and about 15% for Wegovy, which is why Mounjaro is usually the" } ], "sha256": "0e5912c403ccbc3af088724938416b455e318b04b56fdab1143692d2dafbe4fe" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "perplexity", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "raglutide injection with about 5–8% average weight loss, while Wegovy is described around 15–17% and Mounjaro around 18–22%.[2][6]" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "raglutide injection with about 5–8% average weight loss, while Wegovy is described around 15–17% and Mounjaro around 18–22%.[2][6]" } ], "sha256": "bac7237773737fa54858893a6a6b582251ba55023d32d7fd96eefb3d17e92500" }, { "slug": "UAE-C13", "date": "2026-09-25", "window": "before-v4", "engineVersion": 4, "engine": "google", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", 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], "precision": "decimal", "span": "In the STEP-1 trial, participants experienced an average weight loss of 13.7% over 68–72 weeks." } ], "sha256": "25a7cfe0d14859a2366857d4dbc31663bfe70d07c6994e29f8e34ec7aefd7e1d" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "openai", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "ignificant weight loss, with participants achieving an average reduction of approximately 17% of their body weight." } ], "sha256": "8d9c395e35720b9b215fb4c97208c06c6afce25ab3660d1ad26429d0b2703f57" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "openai", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { 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"figures": [ { "text": "[figure beside a withheld sentence of page P61]", "value": null, "decimals": null, "unit": null, "measure": "weight-pct", "category": "label", "matchedRefs": null, "precision": "integer", "span": "[sentence S3 of withheld page P61]." } ], "sha256": "1b9387341ae7d7b4f0e448d1fc474e29940d8f232f870522ea4a960e84242aa9" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "cc1face78c7a1a473c6111ae2a6a326278df44dbd9c2599e7d652a18b8d8f59b" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "The once-daily 25 mg Wegovy pill delivered an average 17% weight loss in clinical trials, with about 1 in 3" }, { "text": "16.6%", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6% compared to Foundayo's 12.4%" } ], "sha256": "38bbe8a645fe20642842c66a41a30fcb61db3d88cd1c0748bd9dacd9e3716d67" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "3732c82a843f69bd5611819dd0d891c4ac11306a1ef1a630fdaf95b622db8551", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "c3e1bee80547b47ce667ea990da2a31e5df82e7a0a7b81a3c0f4a7ee91456f5f" }, { "text": "[Gemini figure text withheld]", "textSha256": "3732c82a843f69bd5611819dd0d891c4ac11306a1ef1a630fdaf95b622db8551", "value": 20, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "c3e1bee80547b47ce667ea990da2a31e5df82e7a0a7b81a3c0f4a7ee91456f5f", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 20% at the stated precision, so it stays no-source. Decisive words: [Gemini answer text withheld]." } } ], "sha256": "b48e526bce763429bf0de76dd9eae9f9a70d8becd6586d5a9eea3b3d59b876b2" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "21%", "value": 21, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEPUP-7.2-tp" ], "precision": "integer", "span": "f 22.5% of their starting body weight, while those taking Wegovy 7.2mg lost an average of 21%." }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to other oral options." } ], "sha256": "84bb053952d5d3fdf93766b8423770cd70771fec89380cc545509fc84d2ecf6d" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q23", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent." } ], "sha256": "8b05957c60f49b4665630230037de51b4d9bd37796b30b9271ddf4fefa8d2dff" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17 percent", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Clinical data from the OASIS 4 trial showed participants achieving an average 17 percent weight reduction when adhering to the 25 mg daily" } ], "sha256": "43b886d28b2fcf3373a1ef74bb2fae1574ba180e90f0fb4d6574d1a8732fefba" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "t alternative to Zepbound is Wegovy (semaglutide), another injectable GLP-1 that produces 15% average body weight loss." }, { "text": "13.6%", "value": 13.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct" ], "precision": "decimal", "span": "The highest 25mg Wegovy pill achieved about 13.6% weight loss in 64 weeks" } ], "sha256": "6da28f3fd48642b6e58b34837e0396045f818f645899aa143d72ab5ed423ea8d" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "The Wegovy group lost an average of roughly 16% of their initial body weight compared to about 6%" }, { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Once-daily 25 mg oral semaglutide demonstrated ~17% mean weight loss with adherence; about 1 in 3 par" } ], "sha256": "31c97383ab0ba636900d181702693b529e3e412d9c2cccb8714425d45d2f7916" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "se more weight with Wegovy compared with Saxenda, with people taking Wegovy losing nearly 16% of their starting weight on average, compared wit" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" } ], "sha256": "cd50ef663d9d2ea20c98f25a3938c8994998b599be605ca46a5bea657c06fbfc" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "dc7aaa377133d3325148feffdfb0cec2b87184c43e00c5eaf5edc950ddf6b1a6", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "fcdb0dd68e23222caa11b4dff535b676517e6fb5292de631ba9aefb2c4222763" }, { "text": "[Gemini figure text withheld]", "textSha256": "dc7aaa377133d3325148feffdfb0cec2b87184c43e00c5eaf5edc950ddf6b1a6", "value": 19, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEPUP-7.2-pct-fda", "E-STEPUP-7.2-pct" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "fcdb0dd68e23222caa11b4dff535b676517e6fb5292de631ba9aefb2c4222763" }, { "text": "[Gemini figure text withheld]", "textSha256": "21788f57e84dd2403ecb3a14145c5315f5cc29d0a74c69747c52de54c7b64358", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "4e5ad4eb0c40e8affbf271a38848540baed04e55e97439001e81d5325b2b5b7b" } ], "sha256": "3eb4a808ba38e17983e8890ae85eb55fad6a1293996477c823acb8bf33128342" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Expected weight loss | Around 15% on average over roughly 68 weeks when combined wi" } ], "sha256": "d51041c6c9b4d5e87a5245dfa1461fa5c29377f0b55277f223d4ea50d94c049b" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15.8%", "value": 15.8, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP8-pct" ], "precision": "decimal", "span": "| Average weight loss | About 15.8% over 68 weeks in a direct comparison | About 6.4%" } ], "sha256": "31e811e50ef112bb95fdf3ef850a93ac856656d30b72465dcc390c1900cc516d" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "12–17%", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "ght loss | Generally higher—around 20% or more in high-dose studies[1][3] | Approximately 12–17% in commonly cited studies[1][3] |", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Table column Wegovy: \"Approximately 12-17% in commonly cited studies\"; endpoint 12 matches no reference (17 matched). Decisive words: \"… higher—around 20% or more in high-dose studies[1][3] | Approximately 12–17% in commonly cited studie…\"." } }, { "text": "12–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "ght loss | Generally higher—around 20% or more in high-dose studies[1][3] | Approximately 12–17% in commonly cited studies[1][3] |" } ], "sha256": "87357a1e3e42a506c9feac23738452a72447cc08b1b7f10f849aae42cf8f6fe9" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "077a7f7ed5c2d745b6bf02c8384489cde13b77af6e9ff35f482ba8d4747c4de5" } ], "sha256": "f3b59237dfe87c7a8a7f7266a394b8bc5a1b8a97236dfe402e046d598381be51" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "13.7%", "value": 13.7, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP9-pct" ], "precision": "decimal", "span": "k comparison, tirzepatide produced approximately 20.2% average weight loss, compared with 13.7% for Wegovy.[2] Therefore, if both were equally ac" }, { "text": "14%", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "| Average weight loss | About 14% in the head-to-head trial[2] | About 20% in the h" } ], "sha256": "b49a4058146ea6107eba9cff27cf1db28a22b749d21dac591397380233bc2750" }, { "slug": "UAE-C19", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f04", "choiceQuestion": false, "outcome": "label", "figures": [ { "text": "10–17%", "value": 10, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP2-pct", "L-STEP6-1.7-pct", "L-STEPUPT2D-2.4-pct" ], "precision": "integer", "span": "Eligible users may lose roughly 10–17% of body weight over about a year, provided they t" }, { "text": "10–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Eligible users may lose roughly 10–17% of body weight over about a year, provided they t" } ], "sha256": 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weight over 68 weeks when paired wi" } ], "sha256": "31e8d8c0ff37c3762ee50cb730003f34aa69fc2a7e06e4961e0706c470ed5ef8" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "no-source", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Trial data show average weight loss of about 16.6 per cent with the oral form, comparable to the 2.4mg injec" }, { "text": "5 to 11 pounds", "value": 2.3, "decimals": 0, "unit": "lb", "measure": "weight-kg", "category": "no-source", "matchedRefs": [], "precision": "converted", "span": "to 21 pounds, while semaglutide effects are generally less pronounced, ranging from about 5 to 11 pounds", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "uncertain: semaglutide \"about 5 to 11 pounds\" (5 lb = 2.3 kg), compared with tirzepatide for blood sugar control and weight; no Wegovy named in the answer and a diabetes-style context, but plain semaglutide counts under S6. No kg reference within 0.5 of 2.3 kg. Decisive words: \"…semaglutide effects are generally less pronounced, ranging from about 5 to 11 pounds\"." } }, { "text": "5 to 11 pounds", "value": 5, "decimals": 0, "unit": "lb", "measure": "weight-kg", "category": "no-source", "matchedRefs": [], "precision": "converted", "span": "to 21 pounds, while semaglutide effects are generally less pronounced, ranging from about 5 to 11 pounds", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "uncertain: semaglutide \"about 5 to 11 pounds\" (11 lb = 5.0 kg), compared with tirzepatide for blood sugar control and weight; no Wegovy named and a diabetes-style context, but plain semaglutide counts under S6. C-OCTANE-kg 4 is 1.0 kg away, so no match. Decisive words: \"…semaglutide effects are generally less pronounced, ranging from about 5 to 11 pounds\"." } } ], "sha256": "01ba815e343955277001cb446742a448e754a1c4b4f43c0c46fb75fe7eb8e5db" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "21%", "value": 21, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEPUP-7.2-tp" ], "precision": "integer", "span": "f 22.5% of their starting body weight, while those taking Wegovy 7.2mg lost an average of 21%." }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "7081bee29842f6678efe5d6e810a2cf8a23222770bcec65ea7f8aa7061ed86bb" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q23", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "ed9495e0ef79a465466d2ed2edff18d131bd9f8722347044af88a5f980a56f36" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "t alternative to Zepbound is Wegovy (semaglutide), another injectable GLP-1 that produces 15% average body weight loss." }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." }, { "text": "14.9%", "value": 14.9, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct" ], "precision": "decimal", "span": "Semaglutide (branded as Ozempic for diabetes, Wegovy for weight loss) produces an average 14.9% body weight loss over 68 weeks in the STEP 1 tria" } ], "sha256": "f92b97314977c44465dcf4aed99d88520a814d4a9d9664e01147b4d7ba43e09a" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "In a 68-week study, people taking Wegovy lost nearly 16% of their starting weight, on average, compared wi" } ], "sha256": "0c7ac1c57afd2de0a5b7c4ff43f3e443f6526d9ee39d6ee1f28ec830a09b4656" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" } ], "sha256": "73f438cc3b4b354c80aa964bd0cdee2f73e994e001b1450a100e89b2d761a5bc" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "Once-daily 25 mg oral semaglutide demonstrated ~17% mean weight loss in trials; about 1 in 3 particip" }, { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "The Wegovy group lost an average of roughly 16% of their initial body weight." }, { "text": "21%", "value": 21, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEPUP-7.2-tp" ], "precision": "integer", "span": "tter for weight loss than Saxenda, as after 72 weeks, there was an average weight loss of 21% on Wegovy." } ], "sha256": "722498c69507a9effccf4b1e6a60600f6780b478ac9449f0dcdcbc81041e1eae" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f01", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Expected weight loss | Trial data generally show roughly 15–17% average loss over about 68 weeks in eligible adul" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "| Expected weight loss | Trial data generally show roughly 15–17% average loss over about 68 weeks in eligible adul" } ], "sha256": "daaa878b8531ebc9d2a2788fc7be0054be80ae93f9aa62481e58d735055293f0" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Expected weight loss | Around 15% over 68 weeks in the pivotal STEP 1 trial when co" } ], "sha256": "41f5ed07323b01e8c37924bb095b93d26c89c7928e4c7bb11a7faaceb5ba5a12" }, { "slug": "UAE-C20", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": 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"promptId": "uae-f04", "choiceQuestion": false, "outcome": "no-source", "figures": [ { "text": "12–17%", "value": 12, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "no-source", "matchedRefs": [], "precision": "integer", "span": "UAE reports indicate average losses around 12–17% of body weight with appropriate treatment, alongs", "d4": { "verdict": "confirmed", "scriptedCategory": "no-source", "note": "Wegovy mean-effect figure under the Wegovy entry/sentence; no reference value rounds to 12% at the stated precision, so it stays no-source. Decisive words: \"UAE reports indicate average losses around 12–17% of body weight with appr…\"." } }, { "text": "12–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "UAE reports indicate average losses around 12–17% of body weight with appropriate treatment, alongs" } ], "sha256": "1117e52f8f3398902dfe8e03de21cf3c514e26bdc9fbf09e7f657d4f4d4ab60c" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f05", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Weight-loss potential | Higher-dose semaglutide; trials report about 15% average loss over 68 weeks with lifestyle support" } ], "sha256": "31ff5758f5aad07a88f17c46c99f4e733ed4742acb48e505665080fbfd3fa608" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15.8–16%", "value": 15.8, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP8-pct" ], "precision": "decimal", "span": "| Average weight loss in head-to-head evidence | About 15.8–16% after roughly 68 weeks[6][9] | About 6.4% after r" }, { "text": "15.8–16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "| Average weight loss in head-to-head evidence | About 15.8–16% after roughly 68 weeks[6][9] | About 6.4% after r" } ], "sha256": "d86ec53e900048978c076390de03b6f4705298068a6f76de744a92e9c0f4aadc" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f02", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "15%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "| Average weight loss | About 15% over 68 weeks in the STEP 1 trial[1] | About 20%" }, { "text": "14%", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "The head-to-head trial found approximately 20% average weight loss with Mounjaro versus 14% with Wegovy after 72 weeks.[6] This is an average" } ], "sha256": "0eb53a1e54df9bd5b21d7fe70a496c26b2a0d3f48d2916459273dcf4ead8cca4" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "13.7%", "value": 13.7, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP9-pct" ], "precision": "decimal", "span": "| Expected weight loss | About 13.7% at 72 weeks in the standard-dose head-to-head com" }, { "text": "14%", "value": 14, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-OASIS4-pct", "E-STEP9-pct", "E-STEPUPT2D-7.2-tp" ], "precision": "integer", "span": "maximum average weight loss: Zepbound/tirzepatide, with trial averages around 20% versus 14% for standard-dose Wegovy.[1][3]" } ], "sha256": "bd55cf31acbea980382c2afc9815d9cef76a5ef3a6c9d6a2e438d4688b750220" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "uae-q27", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": "b5f6dbae04bd764b0c2f3cb796e404ffdf77fb4cac171d72ec7fa6a2077da252", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "3f5adfb6db64024bb7794a29e8670a53858c47e15d513e46f7f7406f8f39b3c2" } ], "sha256": "ad7ff9b5b59965d59a81f6dd3aa9cf0a01bdc934258864db5939814dcb22acf0" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q04", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "trial data show average weight loss of about 16.6 per cent with the oral form" } ], "sha256": "f7df556b576b9dd523871bb52e640af0b8f889157f3a8a5351ed46e2d19ddebf" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" } ], "sha256": "1a5aa3cde6385e90100177229e2f3f6e97e68ab565bd047128168c2f24714a3a" }, { "slug": "UAE-C21", "date": "2026-10-09", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "uae-q29", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "[Gemini figure text withheld]", "textSha256": 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"L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "ht with Wegovy compared with Saxenda—in a 68-week study, people taking Wegovy lost nearly 16% of their starting weight, on average, compared wi" } ], "sha256": "a0f6b3089734d5b9915db28f17e7a5dc72406960ae340035a15da45de6c715ec" }, { "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-q23", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "Oral Wegovy reduces body weight by up to 16.6 per cent" } ], "sha256": "baac4087903dde1dca8b5712cb80c41bca1e64ca70e423da2763597809f0c751" }, { "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f06", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16%", "value": 16, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP3-pct", "L-STEPUP-2.4-pct-fda", "L-TEENS-bmi-pct", "E-STEP8-pct", "E-STEPUP-2.4-pct" ], "precision": "integer", "span": "eight compared to those using Saxenda, with the Wegovy group losing an average of roughly 16% of their initial body weight compared to about 6%" }, { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." } ], "sha256": "82324070e298932ebc7b09a454ee2cf03c12bc7fa8d59a0aa63d3c022a53617e" }, { "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "uae-f03", "choiceQuestion": true, "outcome": "label", "figures": [ { "text": "16.6 per cent", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "ble GLP-1 therapies remain more effective, with oral Wegovy reducing body weight by up to 16.6 per cent compared to Foundayo's 12.4 per cent." }, { "text": "16.6%", "value": 16.6, "decimals": 1, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-OASIS4-tp" ], "precision": "decimal", "span": "- Need maximum weight loss results (20%+ vs. 16.6% for Wegovy)" } ], "sha256": "eac14107a8db999f368075880604e34ca6697b6afc58462d9466e0a56b35681e" }, { "slug": "UAE-C23", "date": 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"figures": [ { "text": "15–17%", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "cted weight loss | Stronger evidence at the obesity dose; clinical studies report roughly 15–17% average loss in suitable patients.[6][8] | Can pr" }, { "text": "15–17%", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "cted weight loss | Stronger evidence at the obesity dose; clinical studies report roughly 15–17% average loss in suitable patients.[6][8] | Can pr" } ], "sha256": "8c6eef8a42c0385974c2f02d9368d9ffe8b68323d1f33dc1ec301390f8976da2" }, { "slug": "UAE-C23", "date": "2026-10-11", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "uae-f05", "choiceQuestion": true, "outcome": 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the stated precision, so it stays no-source. Decisive words: [Gemini answer text withheld]." } }, { "text": "[Gemini figure text withheld]", "textSha256": "97b24cab3d48e47c11cff2598b6c26d69a6d5a834d270d8711c2e3662c310e90", "value": 15, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "L-STEP1-pct", "L-TEENS-wt-pct", "E-STEP5-pct", "E-STEP9-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "c7471ac3b299f62237ffae40cf817fe6d265c76a7bd161aa047b8ee46703ecb0" }, { "text": "[Gemini figure text withheld]", "textSha256": "9ff68d1fb292cbc96dca1d6f63353538176ff2bd5ec29c468ffa45da65a135fc", "value": 17, "decimals": 0, "unit": "%", "measure": "weight-pct", "category": "label", "matchedRefs": [ "E-STEP1-tp", "E-STEP5-tp", "E-STEP8-tp", "E-OASIS4-tp" ], "precision": "integer", "span": "[Gemini answer text withheld]", "spanSha256": "9c59fdad6f836339fdd98dbe94dceb855bb53b1e4cf8ab2454b27cf4e0d26df3" } ], "sha256": 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"e5-first-line-with-metformin", "span": "n in adults with type 2 diabetes - SGLT2 inhibitors are now first-line add-on to metformin in any patient with established cardiovascular disease, heart failure or chronic kidney disease, regardless of HbA1c - Widely availabl", "note": "First-line add-on to metformin regardless of HbA1c (high-risk patients).", "sha256": "91708387d7eb858bc456d6ea0537affbbdc2c042649bacd6f23c436ed00a79a7" }, { "slug": "SG-C17", "date": "2026-10-02", "window": "during", "engineVersion": 5, "engine": "google", "promptId": "sg-f06", "choiceQuestion": false, "terms": [ "first-line" ], "code": "e5-first-line-with-metformin", "span": "[Gemini answer text withheld]", "spanSha256": "85af85385cd9e736aa8460a98f8a0697e19e076c4d6d280cc80322fb5a67c45b", "note": "First-line add-on to metformin, high-risk patients, regardless of HbA1c.", "sha256": "8ba3931412582486d605f9d93f6287af253eb69da74189cd205ceb8f05bb3454" }, { "slug": "SG-C17", "date": "2026-10-02", "window": "during", 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"sg-q11", "choiceQuestion": true, "terms": [ "initial" ], "code": "e5-first-line-with-metformin", "span": "s are used for **type 2 diabetes**, and Forxiga also has an **initial combination with metformin** indication.[1][2] - SGLT2 inhibitors can cause **genital/urinary infections**, **low blood", "note": "Initial combination with metformin (Forxiga indication).", "sha256": "62907e90b48c6e33fd5b318fdde42e012adeb0cb6289d9c1c833add18de221c4" }, { "slug": "SG-C19", "date": "2026-10-06", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q11", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "641d9f7a93505acb1e7d07c3d6dba9cb4fe1fcbf04b8fc381b85cad8c5170b76", "note": "Monotherapy named only for low hypoglycaemia risk; no first-line framing in type 2 diabetes.", "sha256": "c40389ac2107f8bcdd4ad095c43961ec3d80c8fafaa70307e0b8c1e56df93a35" }, { "slug": "SG-C19", "date": "2026-10-06", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q18", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "2b0319cf8f57da91fea696ca847b9242566906a1dee691ab667cc67c4123892f", "note": "Monotherapy named only for low hypoglycaemia risk; no first-line framing in type 2 diabetes.", "sha256": "a7081e190d577bcf517f95bea7df65af14caf1dd79207a9153fb661e514c193f" }, { "slug": "SG-C19", "date": "2026-10-06", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q01", "choiceQuestion": true, "terms": [ "monotherapy", "initial" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "c27662b5c845f715b2f305ab84cdc6bd6071e834279bdc26a314f2ae2f9168a2", "note": "Monotherapy named only for low hypoglycaemia risk; no first-line framing in type 2 diabetes.", "sha256": "e08f7aa0c4da5a69fe51abf670fa00084183c4720c171987d7503306c0e72bca" }, { "slug": 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"2dad30bf6e0e6593d2b850ee4a0705e552f2a0e24eb4e6dc2b0642640f296dc0" }, { "slug": "SG-C19", "date": "2026-10-06", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-f05", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "03e932b6980c1982217131a1e28735315ca66ff0ab6d10c260acbf2494e03fc7", "note": "Indicated as monotherapy or combination; no first-line framing.", "sha256": "1001430b49adfa30bd766ff1a2a93219f77d3655b663d9f306ab117eeb9aa1f2" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q15", "choiceQuestion": false, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "96bfda0d17c6c5ddaaa0ddd8636b14da25c7ccbfbea0f452e133f896f18191b3", "note": "Monotherapy named only for low hypoglycaemia risk; no first-line framing in type 2 diabetes.", "sha256": "fb58f36be64c5204e8887241e944266f27be5aef4cef24353aa311d25793523e" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "sg-q11", "choiceQuestion": true, "terms": [ "initial" ], "code": "e5-first-line-with-metformin", "span": "rand; once daily; heart and kidney benefits; can be used in initial combination with metformin under its Singapore indication.[2][3] | Dapagliflozin tablets were removed from", "note": "Initial combination with metformin (Forxiga indication).", "sha256": "cab94dfd116c775ec82149e549ee022d411cbb5d76553d48b9900ca2160ad5af" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "perplexity", "promptId": "sg-q10", "choiceQuestion": false, "terms": [ "first-line" ], "code": "e5-not-first-line", "span": "**Forxiga — equally serious first-line alternative** - Strong choice when chronic kidney disease or heart failure is part of the t", "note": "Ambiguity A7 (as in the baseline: \"first-line\" within the SGLT2 class, not relative to metformin): \"first-line alternative\" ranks Forxiga against the other SGLT2 brands (second to Jardiance); the answer never places SGLT2 inhibition against metformin or in the type 2 diabetes treatment sequence. Read in full.", "sha256": "cd72e48d25e5e5d315920f0eceec8a93ee0cf028fd705f9659e6191350de2826" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q14", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "f83a8865f16d9339ec945ee2d5bf66d4672a45937c8d07ce97b35afd13ceea89", "note": "Monotherapy named only for low hypoglycaemia risk; no first-line framing in type 2 diabetes.", "sha256": "975ade2ca5d186df25c796a8f823c4221246d7f9009706847b062fd91dee3293" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q03", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "3951c3c00c9b7875b6e361bb6260f2418186c6c04ae8636788076621c2a0898f", "note": "Monotherapy named only for low hypoglycaemia risk; no first-line framing in type 2 diabetes.", "sha256": "28885c95cd9946f49b13677b65e843e64c03943808bf56cc4f20d25e462ff5b0" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "anthropic", "promptId": "sg-q12", "choiceQuestion": true, "terms": [ "initial", "monotherapy" ], "code": "e5-first-line-with-metformin", "span": "e 2 diabetes mellitus, and Forxiga® is also indicated as an initial combination therapy with metformin - **Clinical benefits**: A large observational study found that the benefits of", "note": "Initial combination with metformin (Forxiga indication); monotherapy named as flexibility only.", "sha256": "9c7fc86a12005e2b697278e21eb7f880d0ac340e55b6d54739d94f93328a34dd" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q09", "choiceQuestion": true, "terms": [ "first-line" ], "code": "e5-first-line-with-metformin", "span": "[Gemini answer text withheld]", "spanSha256": "ba8ae7fe027fc5d78f66a558a4776ade2473d702b6cbc45e53fdff5766d074a2", "note": "First-line add-on to metformin, high-risk patients, irrespective of HbA1c.", "sha256": "a4c97b93f967873f397b6dde613526abd3c09febfa9c57e3b055595b28cf83a3" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q04", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "230c31d693ca0a508e4f15227f348cf1aac7f71bfa99dec6c39e336c807976ea", "note": "Indicated as monotherapy or add-on; no first-line framing.", "sha256": "163cb8f4d1b40e29323e47b3d61f5aa7e709d4fe0e52b04cada36adeafa6f9af" }, { "slug": "SG-C20", "date": "2026-10-07", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q08", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "24b4b24df8072062b12d6ddb5961b3c734581902261abe7650e94238b4c7e20f", "note": "Monotherapy named only for low hypoglycaemia risk; no first-line framing in type 2 diabetes.", "sha256": "1951d8a205cd9ddfb22162d75ad6d22a93cd73feafb0ae11595e343421db6e81" }, { "slug": "SG-C21", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q18", "choiceQuestion": true, "terms": [ "monotherapy", "first-line" ], "code": "e5-first-line-with-metformin", "span": "[Gemini answer text withheld]", "spanSha256": "ff2dae15ac60c7b8f79129e3b87cc54f645f4927f306f2c0ac075d33ecf8ca30", "note": "[Gemini answer text withheld]high-risk patients.", "sha256": "94cb7c6145f8dffcabc7253440f819973e9d1982e45879d12748a25b3302453a" }, { "slug": "SG-C21", "date": "2026-10-08", "window": "after", "engineVersion": 5, "engine": "google", "promptId": "sg-q11", "choiceQuestion": true, "terms": [ "monotherapy" ], "code": "e5-not-first-line", "span": "[Gemini answer text withheld]", "spanSha256": "d4c6ef117eeeb6a2a6a44f87961d0b3355dd1316cba42ad48e4a1e9f41a14f41", "note": "Monotherapy named only for low hypoglycaemia risk; 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