{
  "fetchedAt": "2026-10-02T10:06:28.749Z",
  "readOnly": true,
  "rule": "Regulator records only. Where a record cannot be fetched, status is not-established and is never inferred from news.",
  "entries": [
    {
      "agent": "retatrutide",
      "market": "UAE",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-10-02",
      "regulator": "Emirates Drug Establishment (registered medical product directory)",
      "url": "https://services.ede.gov.ae/drugdirectory?lang=en&IngredientName=retatrutide&PageSize=100",
      "qualifying": "Last dataset refresh: 02 Oct 2026. [IngredientName=retatrutide] Showing 0 0 of 0 results; \"No products match your filters.\""
    },
    {
      "agent": "retatrutide",
      "market": "Singapore",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-08-07",
      "regulator": "Health Sciences Authority (Listing of Registered Therapeutic Products)",
      "url": "https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view",
      "qualifying": "No row naming retatrutide among 5511 registered therapeutic products; listing last updated 2026-08-07T17:43:28+08:00 (HSA updates it about every six months, so registration after that date is not covered)."
    },
    {
      "agent": "retatrutide",
      "market": "US",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-09-30",
      "regulator": "FDA (Drugs@FDA via openFDA)",
      "url": "https://api.fda.gov/drug/drugsfda.json?search=openfda.generic_name:%22retatrutide%22+OR+products.active_ingredients.name:%22retatrutide%22&limit=5",
      "qualifying": "openFDA drugsfda: {\"code\":\"NOT_FOUND\",\"message\":\"No matches found!\"} for retatrutide; dataset last_updated 2026-09-30"
    },
    {
      "agent": "retatrutide",
      "market": "EU",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-10-02",
      "regulator": "EMA / European Commission (EMA medicines dataset)",
      "url": "https://www.ema.europa.eu/en/documents/report/medicines-output-medicines_json-report_en.json",
      "qualifying": "No human-medicine record whose name, INN or active substance contains retatrutide among 2746 records (dataset timestamp 2026-10-02T06:02:04Z); the dataset includes authorised medicines and pending CHMP opinions."
    },
    {
      "agent": "cagrisema",
      "market": "UAE",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-10-02",
      "regulator": "Emirates Drug Establishment (registered medical product directory)",
      "url": "https://services.ede.gov.ae/drugdirectory?lang=en&IngredientName=cagrilintide&PageSize=100",
      "qualifying": "Last dataset refresh: 02 Oct 2026. [IngredientName=cagrilintide] Showing 0 0 of 0 results; \"No products match your filters.\" · [SearchTerm=CagriSema] Showing 0 0 of 0 results; \"No products match your filters.\""
    },
    {
      "agent": "cagrisema",
      "market": "Singapore",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-08-07",
      "regulator": "Health Sciences Authority (Listing of Registered Therapeutic Products)",
      "url": "https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view",
      "qualifying": "No row naming cagrilintide / cagrisema among 5511 registered therapeutic products; listing last updated 2026-08-07T17:43:28+08:00 (HSA updates it about every six months, so registration after that date is not covered)."
    },
    {
      "agent": "cagrisema",
      "market": "US",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-09-30",
      "regulator": "FDA (Drugs@FDA via openFDA)",
      "url": "https://api.fda.gov/drug/drugsfda.json?search=openfda.generic_name:%22cagrilintide%22+OR+products.active_ingredients.name:%22cagrilintide%22&limit=5",
      "qualifying": "openFDA drugsfda: {\"code\":\"NOT_FOUND\",\"message\":\"No matches found!\"} for cagrilintide; dataset last_updated 2026-09-30"
    },
    {
      "agent": "cagrisema",
      "market": "EU",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-10-02",
      "regulator": "EMA / European Commission (EMA medicines dataset)",
      "url": "https://www.ema.europa.eu/en/documents/report/medicines-output-medicines_json-report_en.json",
      "qualifying": "No human-medicine record whose name, INN or active substance contains cagrilintide / cagrisema among 2746 records (dataset timestamp 2026-10-02T06:02:04Z); the dataset includes authorised medicines and pending CHMP opinions."
    },
    {
      "agent": "orforglipron",
      "market": "UAE",
      "status": "approved",
      "approvedOn": "2026-04-02",
      "recordAsOf": "2026-10-02",
      "regulator": "Emirates Drug Establishment (registered medical product directory)",
      "url": "https://services.ede.gov.ae/drugdirectory?lang=en&IngredientName=orforglipron&PageSize=100",
      "qualifying": "Last dataset refresh: 02 Oct 2026. Foundayo 0.8 mg — Active — registered 02 Apr 2026 · Foundayo 14.5mg — Active — registered 02 Apr 2026 · Foundayo 17.2mg — Active — registered 02 Apr 2026 · Foundayo 2.5mg — Active — registered 02 Apr 2026 · Foundayo 5.5mg — Active — registered 02 Apr 2026 · Foundayo 9mg — Active — registered 02 Apr 2026 · [IngredientName=orforglipron] Showing 1 6 of 6 results · Foundayo 0.8 mg — Active — registered 02 Apr 2026 · Foundayo 14.5mg — Active — registered 02 Apr 2026 · Foundayo 17.2mg — Active — registered 02 Apr 2026 · Foundayo 2.5mg — Active — registered 02 Apr 2026 · Foundayo 5.5mg — Active — registered 02 Apr 2026 · Foundayo 9mg — Active — registered 02 Apr 2026 · [SearchTerm=Foundayo] Showing 1 6 of 6 results"
    },
    {
      "agent": "orforglipron",
      "market": "Singapore",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-08-07",
      "regulator": "Health Sciences Authority (Listing of Registered Therapeutic Products)",
      "url": "https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view",
      "qualifying": "No row naming orforglipron / foundayo among 5511 registered therapeutic products; listing last updated 2026-08-07T17:43:28+08:00 (HSA updates it about every six months, so registration after that date is not covered)."
    },
    {
      "agent": "orforglipron",
      "market": "US",
      "status": "approved",
      "approvedOn": "2026-04-01",
      "recordAsOf": "2026-09-30",
      "regulator": "FDA (Drugs@FDA via openFDA)",
      "url": "https://api.fda.gov/drug/drugsfda.json?search=openfda.generic_name:%22orforglipron%22+OR+products.active_ingredients.name:%22orforglipron%22&limit=5",
      "qualifying": "NDA220934 FOUNDAYO: ORIG submission status AP, 20260401"
    },
    {
      "agent": "orforglipron",
      "market": "EU",
      "status": "not-approved",
      "approvedOn": null,
      "recordAsOf": "2026-10-02",
      "regulator": "EMA / European Commission (EMA medicines dataset)",
      "url": "https://www.ema.europa.eu/en/documents/report/medicines-output-medicines_json-report_en.json",
      "qualifying": "No human-medicine record whose name, INN or active substance contains orforglipron / foundayo among 2746 records (dataset timestamp 2026-10-02T06:02:04Z); the dataset includes authorised medicines and pending CHMP opinions."
    }
  ]
}